Molecular mechanisms of the action of Arctigenin in cancer
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This paper summarizes research that supports the view that arctigenin, extracted from Arctium lappa (burdock), has anti-cancer properties. The researchers focused on the molecular pathways used by arctigenin citing studies on how arctigenin causes cell death (apoptosis), prevents metastasis, and inhibits tumor growth. The researchers reviewed toxicological studies as well as studies that tested the interaction of arctigenin and traditional cancer therapies. They concluded that research supports the use of arctigenin as a cancer therapy. They recommend additional clinical trials with humans.
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Published:
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Biomedicine and Pharmacotherapy 108 (2018) 403-407 ©2018 Elsevier Masson SAS
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Attribution:
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Yinghua He, Qiaomei Fan, Tiantian Cai, Wei Huang, Xianze Xie, Yayun wen, Zheng Shi; Department of Pharmacy, The First Affiliated Hospital of Zhejiang Chines Medicine University, Zhejiang, China, Department of Pharmacy Zhejiang International Exchange Center of Clinical Traditional Chinese Medicine, Zhejiang, China, and Department of Pharmacy, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Zhejiang, China
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Link:
https://www.sciencedirect.com/science/article/pii/S0753332218330580