Arctium Species Secondary Metabolites Chemodiverity and Bioactivities
This study focused on the biological activities and chemistry of the secondary metabolites found in the Arctium species, including Arctium lappa (burdock). According to the authors, more than 200 non-volatile compounds have been isolated from Arctium genus including chemical compounds like lignans, terpenoids, sterols, flavonoides, phenolics, lactones, polyacetylenes, quinic acids and sugars. Lignans, are the most characteristic compound and mainly contain arctigenin. The authors concluded that the Arctium species has the potential to be used in a variety of therapies because the isolated compounds demontrate antipyretic, antimicrobial, diuretic, diaphoretic, hypoglycaemic, antioxidant, anti-inflammatory, anti-hepatotoxicity, antiulcer, antimutagenicity, and antitumour activities.
Published:
Frontiers in Plant Science, published July 9, 2019 doi: 10.3389/fpls.2019.00834
Attribution:
Dongdong Wang¹ ² ᶟ, Alexandru Sabin Badarau⁴, Mallappa Kumara Swamy⁵, Subrata Shaw⁶, Pilippo Maggi⁷, Luiz everson da Sliva⁸, Victor Lopez⁹ ¹⁰, Andy Wai Kan Yeung¹¹, Andrei Mocan¹² ¹ᶟ and Atanas G. Atanasov² ᶟ ¹⁴; ¹The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China, ² Department of Molecular Biology, Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland, ᶟDepartment of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Vienna, Austria, ⁴Department of environmental Science, Faculty of Environmental Science and Engineering, Babes-Bolyai University, Cluj-Napoca, Romania, ⁵Department of Biotechnology, East West First Grade College of Science, Bengaluru, India, ⁶ Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge MA, USA, ⁷ School of Pharmacy, University of Camerino, Camerino, Italy, ⁸ Postgraduate Program in Sustainable Territorial Development, Federal University of Parana, Curitiba, Brazil, ⁹ Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gallego, Spain, ¹⁰Instituto Agroalimentario de Aragon-IA2, CITA-Universidad de Zaragoza, Zaragoza, Spain, ¹¹ Oral and Maxillofacial Radiology, Applied Oral Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China, ¹² Department of Pharmaceutical Botany, faculty of Pharmacy, luliu Hatieganu University for Medicine and Pharmacy, Cluj-Japoca, Romania, ¹ᶟ Laboratory of Chromatography, Institute of Advanced Horticulture Research of Transylvania, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania, ¹⁴ Institute of Neurobiology, Bulgarian academy of Sciences, Sofia, Bulgaria
Link:
https://www.frontiersin.org/articles/10.3389/fpls.2019.00834/full